Unforgettable Once-in-a-Lifetime Trips Around The World

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Searching for epic once in a lifetime trips that will leave you with nothing but incredible memories?

Antarctica

These aren’t your everyday vacations – they’re extraordinary journeys that deserve a spot at the top of your travel bucket list.

From tracking gorillas in misty African forests to watching the northern lights dance above your glass igloo, discover 15 remarkable unique trips that are worth experiencing at least once.

Most Epic Once-in-a-Lifetime Trips Around The World

Discover these 15 unique trip ideas to experience at least once in your lifetime below.

1. Japan Cherry Blossom Journey

Japan Cherry Blossoms

Among the best once-in-a-lifetime trips, exploring Japan during sakura season captivates visitors as they follow the cherry blossom bloom from south to north.

Time your visit between late March and early April, starting in Tokyo’s Ueno Park before heading to Kyoto’s poetic Philosopher’s Path.

Cherry Blossom Kyoto Japan

Stay in traditional ryokans, participate in hanami (flower viewing) parties with locals, and witness the beauty of blossoms illuminated at night in ancient temple gardens.


2. Driving Iceland’s Ring Road

Iceland

This 828-mile circuit around the island ranks high among once-in-a-lifetime holiday ideas, revealing a new natural wonder around every bend.

Chase waterfalls like Seljalandsfoss and Skógafoss, walk on diamond beaches, and soak in geothermal pools.

Diamond Beach, Iceland

Time your journey for summer to experience the midnight sun or winter for northern lights, staying in remote farmhouses for a unique experience.


3. Luxury Maldives Escape

Maldives

Among unique trips, the Maldives offers an unparalleled overwater villa experience that defines paradise.

Choose an atoll known for its house reef, where you can step directly from your villa into crystal-clear waters teeming with marine life.

Maldives beach with a toddler

Book a villa with a glass floor to watch fish swim beneath your feet, arrange private sandbank dinners, and experience night snorkeling with bioluminescent plankton.


4. Track Mountain Gorillas in Rwanda

Gorillas of Volcanoes National Park in Rwanda

Tracking mountain gorillas in Rwanda’s Volcanoes National Park creates once-in-a-lifetime holidays unlike any other.

Trek through misty bamboo forests with expert guides to spend a precious hour with these gentle giants.

The experience of making eye contact with these magnificent creatures in their natural habitat is simply unforgettable.


5. Great Barrier Reef Discovery

Great Barrier Reef Australia

Once-in-a-lifetime destinations don’t come more vibrant than Australia’s Great Barrier Reef.

Scuba Diving in Great Barrier Reef

Base yourself in Port Douglas for access to the pristine Outer Reef sites like Agincourt and Opal Reef, where you can dive or snorkel in clear waters teeming with marine life.


6. Expedition to Antarctica

Antarctica, Antarctic Peninsula, Danco Island. Gentoo penguin courtship.

Among unique trips, an Antarctic expedition stands as the ultimate adventure.

Cruise through the Drake Passage on a small expedition ship, watching albatrosses soar alongside as you enter the last pristine continent.

Antarctica

Zodiac cruise between towering icebergs, walk among vast penguin colonies, and kayak alongside curious whales.

Every day brings new adventures, from camping on the Antarctic Peninsula to polar plunges in thermal suits.


7. Serengeti Migration Safari

Serengeti in Tanzania

One of the best once-in-a-lifetime trips puts you front row for nature’s greatest show.

Time your visit between July and October to witness enormous herds crossing the Mara River, staying in mobile camps that follow the migration.

Serengeti Tanzania

Wake to the sounds of the savanna, take sunrise balloon rides over the endless plains, and enjoy sundowners while watching lions prepare for their nightly hunt.


8. Finnish Lapland Northern Lights Adventure

Glass Igloo in Finland

Arctic magic defines this once-in-a-lifetime holiday as you stay in a glass-roofed igloo surrounded by snow-laden forest, watching the aurora dance overhead from your bed.

Husky safari in Finland

Days are filled with husky sledding, reindeer encounters, and ice fishing, while evenings bring fireside stories of Sami culture and star-filled skies in the pristine polar night.


9. Alaska Passage Cruise

Alaska Passage Cruise

Navigate through pristine fjords and alongside massive glaciers on this remarkable journey.

Choose a small ship to access narrow inlets and remote bays where whales breach and bears fish along the shoreline.

Glacier Bay National Park Alaska

Stop at native Tlingit villages, kayak among seals, and listen to the thunderous calving of glaciers in places like Glacier Bay National Park.


10. Trek to Machu Picchu

Machu Picchu

The classic Inca Trail trek remains a defining once-in-a-lifetime holiday idea.

Spend four days hiking ancient stone paths through cloud forests and mountain passes, each day revealing new Incan ruins.

Machu Picchu

Camp beneath star-filled skies before arriving at the Sun Gate at dawn for your first glimpse of this magnificent citadel emerging from the mist.


11. See the Pyramids of Giza and Cruise the Nile

Egypt Pyramids

Experience ancient wonders in timeless luxury on this Egyptian odyssey.

Begin at the pyramids at sunrise before the crowds arrive, then board a traditional dahabiya for an intimate cruise between Luxor and Aswan.

Boat driving on river Nile in Aswan, Egypt

Visit temples at dawn and dusk, dine on deck beneath star-filled skies, and watch local life unfold along the riverbanks just as it has for millennia.


12. Trans-Siberian Railway Journey

Trans-Siberian Railway

Spanning eight time zones across Russia, this legendary rail journey defines adventure.

Travel aboard the luxury Golden Eagle train from Moscow to Vladivostok, stopping at remote villages and Lake Baikal, the world’s deepest lake.

Share stories with fellow travelers in the bar car, watch endless birch forests roll by, and experience the vastness of Siberia in unparalleled comfort.


13. Wadi Rum Desert & Petra Journey

Most famous landmarks in the world - Petra Jordan

Jordan’s most dramatic landscapes create an otherworldly adventure.

Sleep under stars in a luxury desert camp in Wadi Rum, take sunrise camel rides through red sand dunes, and enjoy traditional Bedouin hospitality.

Wadi Rum Jordan

At Petra, enter through the Siq at dawn to see the Treasury gilded by first light, then explore hidden monasteries and tombs in the rose-red city, walking in the footsteps of ancient civilizations.


14. Galapagos Islands Adventure

Galapagos Islands of famous marine iguanas

Darwin’s living laboratory offers a unique wildlife experience unlike anywhere else on Earth.

Cruise on a small expedition ship to visit different islands, each with unique species that show no fear of humans.

Galapagos Islands

Snorkel with playful sea lions, watch giant tortoises roam freely, and observe blue-footed boobies performing their mating dance in this remarkable archipelago.


15. Trek Patagonia’s Torres del Paine Circuit

Torres del Paine, Patagonia, Chile

Where jagged peaks meet windswept plains, Torres del Paine’s eight-day circuit trek delivers Patagonia at its most dramatic.

Circle the massive granite towers on the full circuit, staying in refugios or camping beneath southern stars.

Patagonia's Torres del Paine Circuit

Cross mountain passes, walk alongside glaciers, and spot condors in this pristine wilderness, where every vista seems more breathtaking than the last.


Final Thoughts on The Most Unique Trips to Take in Your Lifetime

These extraordinary journeys represent just a glimpse of what our wonderful world has to offer.

Whether you’re dreaming of Arctic adventures or tropical paradise escapes, each destination promises experiences that will forever change how you see the world.

Discover more inspiration:

Once in a Lifetime Destinations
Once in a Lifetime Bucket List Travel Ideas
Photo of author

Jolene Ejmont

Originally from South Africa, now living in Australia, Jolene is a wife and a mother to three beautiful daughters. Together with her family, she is embarking on a journey towards changing her current stress-filled life to one focusing on her dreams and her passion for travel. She wants to share her stories in the hope to inspire you to chase your own dreams!